Equipment

Peptide synthesis facility:

The lab is equipped with a 433A peptide synthesizer, as well as a Gilson preparative HPLC for peptide purification and an applied biosystems Voyager DE-Pro MALDI-TOF mass spectrometer.

We have a new, cool microwave assisted peptide synthesizer!
* Microwave energy drives biochemical reactions to completion up to 10 times faster than by conventional methods, resulting in peptides of greater purity than can be produced under conventional methods. Reactions are not just faster; they are more complete when driven by microwave energy. The unique utilization of microwave energy gives the unprecedented ability to synthesize peptides that were previously inaccessible by conventional synthetic methods. (Read more at CEM)

We also got a new preperative HPLC, and and a new analytical HPLC!

Biophysics:

We have a Perkin-Elmer LS55 fluorimeter, equipped with a Hamilton syringe dispenser for titrations and binding studies.

We also have a Shimadzu UV-Vis spectrophotometer, in which, among other things, we measure protein and peptide concentrations.

We have access to the 600 MHz NMR spectrometer, which is located at the Wolfson Center for Structural Biology, in the NMR lab headed by Dr Deborah Shalev, and to the CD machine in the institute of chemistry.

We are the proud owners of a new MicroCal isothermal titration calorimeter (ITC)!
* Isothermal Titration Calorimetry (ITC) is the gold standard for measuring biomolecular interactions. ITC simultaneously determines all binding parameters in a single experiment information that cannot be obtained from any other method.
* The ITC200 system is the most sensitive ITC available. With its reduced size and associated sample quantity requirements, the iTC200 is significantly faster than previous models. (Read more at MicroCal)

[Click here for more photos of the equipment..]