Welcome to Assaf Friedler's lab page
ברוכים הבאים לאתר המעבדה של אסף פרידלר

Our lab is a part of the Institute of Chemistry at the Hebrew University of Jerusalem

We have set an interdisciplinary platform for the study of protein-protein interactions, encompassing Organic Chemistry, Biophysics, Molecular and Theoretical Biology [Learn more]

Prof. Friedler is the Vice-Rector of the Hebrew University


  • A new paper by Koushik in ChemMedChem! Covalent Inhibition of HIV-1 Integrase by N-Succinimidyl Peptides
  • A new paper by Manish in Scientific Reports! The Ec-NhaA antiporter switches from antagonistic to synergistic antiport upon a single point mutation
  • A new paper by Hadar in Chemical Science! Differential effects of Zinc binding on structured and disordered regions in the multidomain STIL protein
    For more info, check out our publications

  • Recent Events:

  • A new lecture by Assaf about intrinsically disrordered proteins (IDPs) in Rambam hospital (in Hebrew)
  • A new interview with Assaf for the MedChemNet website (of Future Medicinal Chemistry)
  • A new way to induce programmed cell death
    [Press release] [Article (hebrew)] [Paper]
  • The Friedler group is supported by a starting grant from the ERC

    The Friedler group is part of the WntsApp Marie Curie Initial Training Network

    The Friedler group is part of the Minerva Center for Bio-Hybrid Complex Systems